3. Targeted Cancer Therapy: Monoclonal Antibodies and Small-Molecule Anti-Cancer Agents

Only available as part of a package

Outline

  • Introduction to Targeted Therapy
    •  Definitions and History
  • Monoclonal Antibodies 
    • Definition, Discovery  
    • Mechanism of Action 
    • Drug Classes 
    • Antibody-Drug Conjugates
  • Small-Molecule Agents 
    • Definition and History 
    • Tyrosine Kinase Inhibitors 
    • Other Small Molecules
  • General Approach for APs 
    • Understanding Targeted Therapies 
    • Obtaining Consent 
    • Considerations for Special Populations

After completing this educational activity, participants should be able to:

  • Describe the mechanisms of action for common targeted therapies, including monoclonal antibodies and small-molecule targeted agents
  • Describe the unique characteristics of common classes of targeted therapies
  • Develop an approach for understanding new agents in this rapidly growing field

Jennifer Jacky

MSN, ARNP, AOCNP®

Fred Hutchinson Cancer Center, University of Washington

Ms. Jacky is a is a board-certified oncology nurse practitioner specializing in thoracic and head and neck malignancies. She works as an APP lead at the Fred Hutchinson Cancer Center. Her interests include clinical trials, optimizing symptom control, and primary palliative care.

Jennifer Jacky has no relevant financial relationships to disclose.

Gabrielle Zecha

PA-C, MHA

Kaiser Permanente - Hawaii

Ms. Zecha is a board-certified PA who works in community oncology. She has spent her career in oncology in a variety of settings and subspecialties including both academic medicine and outpatient community oncology. Her experience includes stem cell transplant, solid tumor, and both classical and malignant hematology.  

Gabrielle Zecha has no relevant financial relationships to disclose.

Key:

Complete
Failed
Available
Locked
Introduction to Targeted Therapy (5 min.)
Open to view video.  |  5 minutes
Open to view video.  |  5 minutes
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Introduction to Targeted Therapy - Knowledge Check
1 Question  |  Unlimited attempts  |  0/1 points to pass
1 Question  |  Unlimited attempts  |  0/1 points to pass Knowledge Check grades DO NOT COUNT towards earning your CE certificate. This is your opportunity to test your knowledge. Please note: You will be informed that you passed at the end of the Knowledge Check.
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Monoclonal Antibodies (14 min.)
Open to view video.  |  14 minutes
Open to view video.  |  14 minutes
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Monoclonal Antibodies - Knowledge Check
1 Question  |  Unlimited attempts  |  1/1 points to pass
1 Question  |  Unlimited attempts  |  1/1 points to pass Knowledge Check grades DO NOT COUNT towards earning your CE certificate. This is your opportunity to test your knowledge. Please note: You will be informed that you passed at the end of the Knowledge Check.
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Bispecific Antibodies (6 min.)
Open to view video.  |  3 minutes
Open to view video.  |  3 minutes
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Bispecific Antibodies - Knowledge Check
2 Questions  |  Unlimited attempts  |  0/2 points to pass
2 Questions  |  Unlimited attempts  |  0/2 points to pass Knowledge Check grades DO NOT COUNT towards earning your CE certificate. This is your opportunity to test your knowledge. Please note: You will be informed that you passed at the end of the Knowledge Check.
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Antibody–Drug Conjugates (6 min.)
Open to view video.  |  6 minutes
Open to view video.  |  6 minutes
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Antibody–Drug Conjugates - Knowledge Check
2 Questions  |  Unlimited attempts  |  0/2 points to pass
2 Questions  |  Unlimited attempts  |  0/2 points to pass Knowledge Check grades DO NOT COUNT towards earning your CE certificate. This is your opportunity to test your knowledge. Please note: You will be informed that you passed at the end of the Knowledge Check.
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Small-Molecule Agents (19 min.)
Open to view video.  |  19 minutes
Open to view video.  |  19 minutes
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Small-Molecule Agents - Knowledge Check
4 Questions  |  Unlimited attempts  |  0/4 points to pass
4 Questions  |  Unlimited attempts  |  0/4 points to pass Knowledge Check grades DO NOT COUNT towards earning your CE certificate. This is your opportunity to test your knowledge. Please note: You will be informed that you passed at the end of the Knowledge Check.
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General Approach for APs (6 min.)
Open to view video.  |  6 minutes
Open to view video.  |  6 minutes
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Targeted Cancer Therapy Monoclonal Antibodies and Small-Molecule Anti-Cancer Agents - Post Test
13 Questions  |  Unlimited attempts  |  10/13 points to pass
13 Questions  |  Unlimited attempts  |  10/13 points to pass This Post Test counts towards your CE Certificate. You must answer at least 10 of 13 questions correctly to earn credit for this module. You have unlimited attempts to pass the Post Test.
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